The main focus of my research over the past two decades has been the molecular genetics of glaucoma. In 1993 my research group described the first genetic linkage for open angle glaucoma (GLC1A). Subsequently, in a 1997 Science paper, we reported that mutations in the myocilin gene at the GLC1A locus caused juvenile glaucoma and 3 – 5% of adult onset open angle glaucoma. I also a coauthored the first papers describing the PITX2 and FOXC1 genes for the Axenfeld-Rieger syndrome, and maintain a webpage to teach gonioscopy.