Arlene Drack

MD

Depts of Ophthalmology and Visual Sciences, and Pediatrics

My research focuses on inherited eye diseases that affect children, particularly in the development of novel treatments. A research project of particular interest is the development and application of mouse models of retinal degeneration. We use subretinal injection of molecules to evaluate treatment in mouse models of retinal degenerations, in preparation for future human trials.

I am a Principal Investigator in the Phase III RPE65 LCA gene therapy trial being conducted at the University of Iowa and CHOP. My clinical skills as an ophthalmic surgeon and electrophysiologist bring important translational aspects to her laboratory studies of treatment in mouse models of human genetic eye disease, with a special focus on Bardet Biedl Syndrome.