Scientists at the WIVR recently published a manuscript in the high impact journal, Progress in Retinal and Eye Research, titled "Complement activation and choriocapillaris loss in early AMD: Implications for pathophysiology and therapy." LINK This manuscript reviews new data showing vascular loss as a very early event in age-related macular degeneration, proposes a hypothesis for how genetic risk factors lead to AMD, and discusses the implications of this model on the development of new therapies.